Testosterone Therapy

Testosterone is made from cholesterol and is manufactured mainly in the testicles in males and ovaries and adrenal glands in females. And undeniably testosterone has an important function in the body of males and females. Most notably it enhances sex drive, builds muscles and bones, helps maintain self-confidence and the immune system, elevates mood and motivation, among many other important properties.

Deficiency in testosterone results in:

  • decreased libido
  • decreased motivation
  • depression
  • increased risk of suicide
  • decreased confidence and feeling of well being
  • decreased muscle mass
  • increased body fat (especially belly fat) leading to obesity
  • difficulty losing weight, decreases exercise performance and tolerance
  • increased incidence of diabetes
  • possibly even increases the risk of prostate cancer and heart attack

Testosterone should NOT be taken by mouth due to numerous detrimental effects, if taken orally.  Administration of testosterone can occur in a variety of ways. Including by daily gels, weekly injections, or testosterone pellets inserted just beneath the skin about every 4 months. Dr. Arthur Zacco inserts these pellets in about 5-10 minutes in the office with no down time.

Dr. Zacco notes that most patients favor testosterone therapy via pellets over injections or gels.  With  testosterone therapy pellets there are no messy gels or frequent injections.  Pellets allow freedom to focus on things other than testosterone therapy.

When patients receive treatment with daily testosterone therapy gel, they must to avoid contact with their loved ones for a couple of hours after applying gels. Also, when patients are using gels or injections, they have to bring these on vacation which can cause hassles at the airport as testosterone is a controlled substance.

In addition pellet testosterone therapy more closely resembles a steady state of testosterone. Because pellets allow consistent delivery of testosterone. Verses the vast fluctuations in testosterone which is common with the use of gels and injections.  Fluctuating testosterone can result in irritability, fatigue, increased fat, and decreased libido.

When being treated with testosterone pellets, you are only reminded of testosterone treatment every four months when the pellets are inserted during a five to ten-minute office procedure in which Dr. Zacco inserts pellets underneath the skin in the alternating upper outer buttocks.

We also offer the following service – Testosterone Pellets.


ESTROGENS: Estrone (E1), Estradiol (E2), Estriol (E3), 16 OH Estrone, 4 OH Estrone, 2 OH Estrone

Estrogen is responsible for keeping the female and male healthy in too many ways to mention here. However, most notably, it maintains bones and muscle mass, keeps the skin and vaginal mucosa healthy, and minimizes breast sagging.

If a woman or man has a family or personal history of breast cancer, their estrogen metabolism should be evaluated and addressed if needed (16 OH Estrone). If you are having hot flashes and you are over 30 years old, chances are good that you have estrogen deficiency and you could be peri-menopausal (early menopause). Not all women have hot flashes with low estrogen.

For hormone replacement therapy, we prefer bio identical hormones BHRT over non-bio identical hormones. Be careful, plant estrogens, or phytoestrogens, and other hormones derived from plants may be considered “natural” estrogens but are NOT bio-identical. Phytoestrogens are natural but are not the same as human estrogens, so they are NOT bio-identical and should not be used for hormonal replacement.

Estrogen like Testosterone is a hormone made of cholesterol. For women and men taking cholesterol lowering medication, it should be noted that they could have an important impact on lowering estrogen levels. Estrogens should NOT be taken orally as this can result in lowering Growth Hormone (GH) among other problems.

Estrogen can be administered by daily creams and gels or by pellets inserted under the skin that last about 4 months. These pellets are inserted only by Dr. Arthur Zacco in our office in about 15-20 minutes.

Testosterone Therapy

Testosterone Therapy

All About Effective Testosterone Therapy in Raleigh, NC

Testosterone is a main male hormone that impacts a man’s ability to have sex and father a child among other male attributes connected with proper testosterone levels. This hormone is found in both males and females at different levels.

A testosterone deficit in men can result in troubling symptoms and development of adverse health conditions if not treated promptly and effectively.

How Aging Impacts a Man’s Hormone Levels

Much like women that develop hormonal shifts that accompany other signs of menopause when they reach a certain age. Males also develop various adverse health conditions if their testosterone levels become too low.

In males, the drop in hormonal levels, like low T, generally happens gradually as these males get older. This issue is expected to become even more prevalent due to older individuals from both sexes living longer these days.

General Overview of Testosterone Therapy All Males Should Know

Fortunately, there are treatments for low testosterone, or low T, termed testosterone replacement therapy or TRT. This hormone replacement treatment can significantly reverse many of the hormone deficit related issues if given by a doctor trained in hormone optimization therapy and its impact on the aging process in general.

What Does Testosterone Do In the Male Body?

Testosterone is responsible for sexual organ development in males, and this male hormone is responsible for the increased sex drive that males are more prone to have.

This hardworking hormone also regulates other typically male oriented body characteristics, feelings and tendencies such as facial hair growth, muscle strength and growth. Testosterone is known to influence male aggression, regulate libido or sex drive, increase sperm count and stimulates an erection. It also regulates mood, stimulates blood and stem cells in kidneys and bones.

Testosterone interacts with a multitude of complex body responses, organ systems and other hormones. As well it impacts the brain and memory, helps keep middle section body fat from developing, indirectly influences sleep, regulates emotions and moods and keeps heart blood vessels dilated.

Symptoms That Could Indicate Low Testosterone Levels

There are many signs of a lowered testosterone level that individuals should be on the lookout for. Including there following:
  • Sexual dysfunction
  • Lack of libido or sex drive
  • Inability to make or keep an erection
  • Increased anxiety
  • Daytime fatigue and/or nighttime insomnia
  • Depression
  • Memory problems
  • Development of muscle aches & bone/joint related pain or stiffness
  • Lack of energy
  • Increased weight especially fat stores in abdominal area
  • Increases risks for heart attack or stroke
  • Muscle wasting and spasms
  • Increased bruising
  • Body enzyme changes
  • Irregular heart rhythm
  • Prostate growth or changes
  • Male pattern baldness
  • Facial hair growth like beards or mustaches
  • Loss of bone density

Benefits of Undergoing Testosterone Replacement Therapy

Undoubtedly, there are a number of fantastic benefits that undergoing testosterone replacement therapy can give. For instance, an increased sex drive, improved libido, better sleep, absence of adverse mood swings, better memory and overall improved mental focus.

Testosterone at the proper levels increases lean muscle mass and strength. Not only does testosterone aid in keeping a leaner physique, it also stimulates more energy. Additionally it increases sperm count. Another excellent health benefit, it lowers bad cholesterol levels.

Diagnosing Low T & Contributing Factors

Men should keep regular appointments at their family doctor’s office to ensure that hormone levels are not showing a deficit. Because lab tests can help the doctor determine if a lowered testosterone serum level is present. And also whether or not there are any related signs and symptoms to address.

It is important for men to keep all of their doctors, specialists, pharmacist and other healthcare team members updated with a current medication list. Because many drugs cause serious side effects and/or mimic low testosterone by development of issues such as sexual dysfunction and extreme fatigue.

Find out if testosterone therapy and/or hormone optimization would benefit you. Call us at Anti Aging & Functional Medicine to schedule an informative consultation appointment. Browse more about TRT and other anti-aging therapies via https://antiagingraleigh.com.

We offer the following service – Testosterone Pellets.